Benzimidazole derivatives and their use for modulating the...

C - Chemistry – Metallurgy – 07 – D

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C07D 401/10 (2006.01) A61K 31/4184 (2006.01) A61K 31/4439 (2006.01) A61P 25/00 (2006.01) C07D 403/10 (2006.01) C07D 417/10 (2006.01) C07D 417/14 (2006.01)

Patent

CA 2604516

This invention relates to novel benzimidazole derivatives of formula (I), pharmaceutical compositions containing these compounds, and methods of treatment therewith. The compounds of the invention are useful in the treatment of central nervous system diseases and disorders, which are responsive to modulation of the GABA receptor complex, and in particular for combating anxiety and related diseases.

L'invention porte sur de nouveaux dérivés du benzimidazole, de formule (I), sur des préparations pharmaceutiques les contenant, et sur des méthodes de traitement les utilisant. Lesdits composés s'avèrent utiles pour traiter les maladies et troubles du SNC répondant à la modulation du complexe du récepteur GABAA, et en particulier pour combattre l'anxiété et les troubles associées.

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