Benzimidazole derivatives and their use for modulating the...

C - Chemistry – Metallurgy – 07 – D

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C07D 235/06 (2006.01) C07D 401/10 (2006.01) C07D 403/04 (2006.01) C07D 403/10 (2006.01) C07D 405/04 (2006.01) C07D 413/04 (2006.01)

Patent

CA 2647252

This invention relates to novel benzimidazole derivatives of formula (I), pharmaceutical compositions containing these compounds, and methods of treatment therewith. The compounds of the invention are useful in the treatment of central nervous system diseases and disorders which are responsive to modulation of the GABAA receptor complex, and in particular for combating anxiety and related diseases.

Cette invention concerne de nouveaux dérivés de benzimidazole de formule (I), des compositions pharmaceutiques contenant ces composés et des procédés de traitement avec ceux-ci. Les composés de l'invention sont utiles dans le traitement de maladies et troubles du système nerveux central qui sont sensibles à la modulation du complexe récepteur GABAA et en particulier dans la lutte contre l'anxiété et des maladies apparentées.

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