C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 401/04 (2006.01) A61K 31/4184 (2006.01) A61P 31/04 (2006.01) C07D 403/04 (2006.01) C07D 403/14 (2006.01)
Patent
CA 2626685
The present invention relates to compounds of formula (I): or a pharmaceutically acceptable salt thereof, that inhibit bacterial gyrase and/or Topo IV and pharmaceutically acceptable compositions comprising said compounds. These compounds, and compositions thereof, are useful in treating bacterial infection. Accordingly, the present invention also relates to methods for treating bacterial infections in mammals.
La présente invention concerne des composés de formule (I) : ou un sel acceptable du point de vue pharmaceutique de ceux-ci, qui inhibent la gyrase bactérienne et/ou la topoisomérase IV bactérienne ; et des compositions acceptables du point de vue pharmaceutique comprenant lesdits composés. Ces composés, et les compositions de ceux-ci, sont utiles dans le traitement d'une infection bactérienne. Par conséquent, la présente invention concerne également des procédés servant à traiter des infections bactériennes chez des mammifères.
Charifson Paul
Deininger David
Drumm Joseph
Grillot Anne-Laure
Letiran Arnaud
Smart & Biggar
Vertex Pharmaceuticals Incorporated
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