Benzimidazole derivatives, compositions containing them,...

Details Benzimidazole derivatives, compositions containing them,... Benzimidazole derivatives, compositions containing them,...

C - Chemistry, Metallurgy

07

D

C07D 235/08 (2006.01) A61K 31/4184 (2006.01) A61P 25/00 (2006.01) C07D 405/06 (2006.01)

Patent

CA 2539738

Compounds of Formula (I) or pharmaceutically acceptable salts thereof; wherein R1, R2, R3, and R4 are as defined in the specification as well as salts and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.

La présente convention concerne des composés représentés par les formules (IA), (IB) ou des sels de ceux-ci répondant aux normes pharmaceutiques. Dans cette formule, Het, X?1¿, R?1¿, R?2¿, R?3¿, R?3¿¿a? et R?4¿ sont tels que définis dans les spécifications. Cette invention concerne aussi la préparation de compositions pharmaceutiques comprenant ces composés. Ces compositions conviennent pour une thérapie, en particulier dans le domaine de la gestion de la douleur.

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