Benzimidazole derivatives, compositions containing them,...

C - Chemistry – Metallurgy – 07 – D

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C07D 235/08 (2006.01) A61K 31/4184 (2006.01) A61P 25/00 (2006.01) C07D 401/06 (2006.01) C07D 405/06 (2006.01)

Patent

CA 2528924

Compounds of formula (I) or pharmaceutically acceptable salts thereof: wherein R1, R2, R3, R4 and Z are as defined in the specification as well as salts and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.

L'invention concerne des composés de formule (I) ou des sels pharmaceutiquement acceptables de ces composés. Dans ladite formule (I), R¿1?, R¿2?, R¿3?, R¿4? et Z correspondent aux définitions données dans la description. L'invention concerne également des sels et des compositions pharmaceutiques contenant ces composés. Ils sont utiles en thérapie, en particulier dans la gestion de la douleur.

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