C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 235/08 (2006.01) A61K 31/415 (2006.01) A61K 31/4184 (2006.01)
Patent
CA 2256687
The present invention relates to benzimidazole derivatives of formula (I), in which the phenyl moiety is substituted with lower alkyl in 2- and 6-position, which inhibit exogenously or endogenously stimulated gastric acid secretion and thus can be used in the prevention and treatment of gastrointestinal inflammatory diseases.
L'invention concerne des dérivés de benzimidazole représentés par la formule (I), dans laquelle la fraction phényle est substituée par alkyle inférieur aux positions 2 et 6, ces dérivés inhibant de façon exogène ou endogène la sécrétion stimulée d'acide gastrique et pouvant, de ce fait, être utilisés pour la prévention et pour le traitement de maladies inflammatoires gastro-intestinales.
Amin Kosrat
Dahlstrom Mikael
Nordberg Peter
Starke Ingemar
Astra Aktiebolag
Fetherstonhaugh & Co.
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