Benzimidazole derivatives, their production and use

Details Benzimidazole derivatives, their production and use Benzimidazole derivatives, their production and use

C - Chemistry, Metallurgy

07

D

167/208, 260/305

C07D 403/10 (2006.01) A61K 31/395 (2006.01) C07D 235/06 (2006.01) C07D 235/08 (2006.01) C07D 235/12 (2006.01) C07D 401/14 (2006.01) C07D 405/14 (2006.01) C07D 413/14 (2006.01) C07F 9/645 (2006.01) C07F 9/6506 (2006.01)

Patent

CA 2028302

Novel imidazole derivatives of the formula (I): (See formula I) wherein R1 is an optionally substituted alkyl group, R2 and R3 are independently a group capable of forming anion or a group which can be changed thereinto, ring A is benzene ring optionally having, besides the group shown by R2, further substituents, and X shows linkage of phenylene group and phenyl group directly or through a spacer whose atomic chain is not more than 2 and a salt thereof, show antagonistic actions to angiotensin II, thus being useful as therapeutics for cardiovascular diseases.

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