Benzimidazole phosphono-amino acids

Details Benzimidazole phosphono-amino acids Benzimidazole phosphono-amino acids

C - Chemistry, Metallurgy

07

F

C07F 9/6506 (2006.01) C07F 9/40 (2006.01) C07F 9/655 (2006.01) C07F 9/6561 (2006.01)

Patent

CA 2242530

This invention provides a process for the preparation of a compound of formula (I), wherein R1 and R2 are each, independently, hydrogen, alkyl, alkoxy, trifluoromethyl, trifluoromethoxy, methanesulfonylamino, acetylamino, halo, cyano, nitro, or when taken together R1 and R2 represent a methylenedioxy or ethylenedioxy moiety; or a pharmaceutically acceptable salt thereof.

Cette invention a trait à un procédé d'élaboration d'un composé répondant à la formule (I) ou d'un sel de celui-ci, acceptable du point de vue pharmaceutique. Dans la formule (I), R<1> et R<2> représentent, chacun, de manière indépendante, un hydrogène, un alkyle, un alkoxy, un trifluorométhyle, un trifluorométhoxy, un méthane-sulfonylamino, un acétylamino, un halo, un cyano et un nitro ou, s'ils sont pris ensemble, une fraction de dioxyméthylène ou de dioxyéthylène.

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