Benzimidazoles, pharmaceutical compositions containing these...

C - Chemistry – Metallurgy – 07 – D

Patent

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C07D 403/04 (2006.01) A61K 31/41 (2006.01) A61K 31/44 (2006.01) A61K 31/535 (2006.01) A61K 31/54 (2006.01) C07D 235/08 (2006.01) C07D 401/04 (2006.01) C07D 401/14 (2006.01) C07D 403/10 (2006.01) C07D 403/14 (2006.01) C07D 413/12 (2006.01) C07D 417/14 (2006.01) C07D 471/04 (2006.01) C07D 487/04 (2006.01) C07D 513/04 (2006.01) C07D 521/00 (2006.01)

Patent

CA 2060624

The invention relates to compounds of formula I (see above formula) and addition salts thereof. As examples of groups R1, there are mentioned fluorine, chlorine, bromine, alkyl and cycloalkyl and as examples of groups R2 there are mentioned alkyleneimino, alkenyleneimino, malefic acid imido, benzimidazol-2-yl and 4,5,6,7-tetrahydrobenzimidazol-2-yl. R3 represents an alkyl or a cycloalkyl group and R4 represents a carboxyl or 1H-tetrazolyl group. The new compounds have useful pharmaceutical properties and are, in particular, angiotensin antagonists.

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