C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 235/16 (2006.01) A61K 31/415 (2006.01) A61P 7/02 (2006.01) C07D 403/06 (2006.01) C07D 403/12 (2006.01)
Patent
CA 2393916
The invention relates to novel benzimidazoles of general formula (I), wherein Ra to Rc have the meanings given in claim no.1, to their tautomers, their stereoisomers, their mixtures, their prodrugs, their derivatives containing a group which has been negatively charged under physiological conditions instead of a carboxy group; and their salts, especially their physiologically compatible salts with inorganic or organic acids or bases; with valuable properties. The compounds of general formula (I) wherein Rc does not represent an amidino group, are valuable intermediate products for producing amidino compounds of general formula (I) which have valuable pharmacological properties, especially an antithrombotic effect.
L'invention concerne de nouveaux benzimidazoles de la formule générale (I) où R¿a? à R¿c? ont la définition donnée dans la revendication (1), leurs tautomères, leurs stéréoisomères, leurs mélanges, leurs prodrogues, leurs dérivés qui contiennent un groupe chargé négativement dans des conditions physiologiques à la place d'un groupe carboxy, et leurs sels, notamment leurs sels physiologiquement tolérables avec des acides ou des bases inorganiques ou organiques aux précieuses propriétés. Les composés de la formule générale (I) où R¿c? ne représente aucun groupe amidino, représentent de précieux produits intermédiaires destinés à la production des composés amidino de la formule générale (I) ayant de précieuses propriétés pharmacologiques, notamment une action antithrombotique.
Hauel Norbert
Kauffmann-Hefner Iris
Nar Herbert
Priepke Henning
Ries Uwe
Boehringer Ingelheim Pharma Gmbh & Co. Kg
Boehringer Ingelheim Pharma Kg
Fetherstonhaugh & Co.
LandOfFree
Benzimidazoles, the preparation thereof and their use as... does not yet have a rating. At this time, there are no reviews or comments for this patent.
If you have personal experience with Benzimidazoles, the preparation thereof and their use as..., we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Benzimidazoles, the preparation thereof and their use as... will most certainly appreciate the feedback.
Profile ID: LFCA-PAI-O-1380250