C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 403/04 (2006.01) A61K 31/4439 (2006.01) A61K 31/506 (2006.01) A61K 31/55 (2006.01) A61K 31/551 (2006.01) A61P 35/00 (2006.01) C07D 401/14 (2006.01) C07D 403/14 (2006.01)
Patent
CA 2616159
The present invention relates to compounds useful as inhibitors of Aurora, FLT- 3, or PDKl protein kinase. The invention also provides pharmaceutically acceptable compositions comprising said compounds and methods of using the compositions in the treatment of various disease, conditions, or disorders. The invention also provides processes for preparing compounds of the invention.
La présente invention concerne des composé utiles comme inhibiteurs d'Aurora, de FLT-3 ou de la protéine kinase PDK1. L'invention concerne également des compositions pharmaceutiquement acceptables comprenant ces composés ainsi que des méthodes d'utilisation de ces compositions dans le traitement de maladies, d'affections ou de troubles divers. L'invention se rapporte en outre à des procédés de préparation des composés susmentionnés.
Binch Hayley
Everitt Simon
Mortimore Michael
Robinson Daniel
Stamos Dean
Smart & Biggar
Vertex Pharmaceuticals Incorporated
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