Benzimidazoles useful as protein kinase inhibitors

Details Benzimidazoles useful as protein kinase inhibitors Benzimidazoles useful as protein kinase inhibitors

C - Chemistry, Metallurgy

07

D

C07D 409/12 (2006.01) A61K 31/4184 (2006.01) A61K 31/422 (2006.01) A61K 31/4439 (2006.01) C07D 235/30 (2006.01) C07D 401/12 (2006.01) C07D 405/12 (2006.01) C07D 407/12 (2006.01) C07D 409/14 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2464419

Disclosed are substituted benzimidazole compounds of formula (I) wherein R1, R2, R3, R4 and Xa are defined herein. The compounds of the invention are useful for treating diseases and pathological conditions involving inflammation, immunological disorders and allergic disorders. Also disclosed are processes for preparing these compounds and to pharmaceutical compositions comprising these compounds.

L'invention concerne des composés de benzimidazole substitués de formule (I), dans laquelle R¿1?, R¿2?, R¿3?, R¿4? et X¿a? sont définis. On utilise les composés de cette invention pour traiter des maladies et des conditions pathologiques impliquant des inflammations, des troubles immunologiques et allergiques. Cette invention a également trait à des processus de préparation de ces composés et à des compositions pharmaceutiques contenant ces composés.

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