Benzisoxazole compound and use thereof

Details Benzisoxazole compound and use thereof Benzisoxazole compound and use thereof

C - Chemistry, Metallurgy

07

D

C07D 413/06 (2006.01) A61K 31/435 (2006.01) A61K 31/495 (2006.01) A61K 31/535 (2006.01) A61K 31/55 (2006.01) C07D 401/12 (2006.01) C07D 413/12 (2006.01) C07D 413/14 (2006.01) C07D 498/04 (2006.01)

Patent

CA 2116117

Abstract of the Disclosure Benzisoxazole compounds and pharmaceutically acceptable salts thereof, having the formula Image wherein when Image bond between 2- and 3-positions is a single bond, Ra is a group of the formula Image [wherein R is hydrogen, alkyl, alkenyl, cycloalkylalkyl, cyclo- alkylalkenyl, phenylalkyl, phenylalkenyl, naphthylalkyl or naphthyl- alkenyl, A is a straight- or branched chain alkylene, and n is 1, 2 or 3], and Rb is oxygen, and when Image bond between 2- and 3 positions is a double bond, Ra is void and Rb is a group of the formula Image [wherein each symbol is as defined above] or a group of the formula Image [wherein E is oxygen or sulfur and other symbols are as defined above]; and R1, R2, R3 and R4 are as defined in the Specification. The compounds of the present invention inhibit acetylcholinesterase in the central nervous system potently and selectively and/or have strong affinity for sigma receptor. 105

Affiliated with

Also associated with

Rating

Benzisoxazole compound and use thereof does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Benzisoxazole compound and use thereof, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Benzisoxazole compound and use thereof will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1731886