Benzo-1, 4 diazepin-2-one derivatives as phosphodiesterase...

C - Chemistry – Metallurgy – 07 – D

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C07D 243/24 (2006.01) A61K 31/5513 (2006.01) A61P 25/00 (2006.01) C07D 413/04 (2006.01)

Patent

CA 2548318

The invention relates to compounds of formula (I) having PDE2 inhibitory activities, as well as therapeutic methods by administering said compounds, in particular for treating various diseases of the central or peripheral nervous system. It further deals with pharmaceutical compositions comprising said compounds and methods for preparing said compounds. Compounds of general formula (I).

La présente invention se rapporte à des composés répondant à la formule (I) et présentant des activités inhibitrices de PDE2, ainsi qu'à des procédés thérapeutiques consistant à administrer lesdits composés, notamment pour le traitement de différentes pathologies du système nerveux central ou périphérique. L'invention se rapporte également à des compositions pharmaceutiques comportant lesdits composés et à des procédés de préparation de ces composés.

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