Benzo¬4,5| cyclohepta ¬1,2,3-de| pyrido ¬2, 1-a| -...

C - Chemistry – Metallurgy – 07 – D

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260/271.5

C07D 455/04 (2006.01) C07C 61/39 (2006.01) C07D 221/18 (2006.01)

Patent

CA 1108145

AHP-7266 BENZO[4,5]CYCLOHEPTA[1,2,3-de]PYRIDO[2,1-a]ISOQUINOLINE DERIVATIVES HAVING MINOR TRANQUILIZER ACTIVITY ABSTRACT OF THE DISCLOSURE 2,3,4,4a,12,13,13a,14-Octahydro-1H-benzo[4,5]cyclohepta[1,2,3,de]- pyrido[2,1-a]isoquinoline and derivatives of 1,2,4,4a,12,13,13a,14-octahydro-3H- benzo[4,5]cyclohepta[1,2,3-de]pyrido[2,1-a]isoquinolin-3-o1 substituted on position 3 with a lower alkyl group are disclosed. The compounds are use- ful minor tranquilizers. Methods for their preparation are disclosed also. -1-

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