Benzo/a/quinolisidine derivatives and a process for the...

C - Chemistry – Metallurgy – 07 – D

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C07D 471/04 (2006.01) A61K 31/47 (2006.01) C07D 217/14 (2006.01) C07D 221/04 (2006.01) C07D 455/06 (2006.01)

Patent

CA 1059126

Abstract of the Disclosure Processes are described for the preparation of benzo(a) quino- lisidine derivatives of the formula I Image (I) wherein: R1 and R2 each represent hydrogen or a C1-4 alkoxy group, or together for a methylenedioxy group; R3, R4, R5 and R6 which maybe the same or different and stand for hydrogen or a group of the formula -CH2-(CH2)n-R7, at least one of them not being hydrogen, and R7 is a carboxyl group or a carboxylic acid derivative group, and n is 0,1, or 2. These compounds and the pharmaceutically acceptable salts thereof have anti-inflammatory properties.

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