Benzo[b]pyran derivatives useful as external agents for the...

C - Chemistry – Metallurgy – 07 – D

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C07D 311/60 (2006.01) A61K 8/02 (2006.01) A61K 8/49 (2006.01) A61K 8/60 (2006.01) A61Q 19/02 (2006.01) C07H 17/04 (2006.01)

Patent

CA 2318343

To provide an external agent for the skin that not only exhibits excellent effects of prevention and amelioration of skin pigmentation but also has no fear of giving adverse influences to the skin and can be used safely, there is added to an external agent for the skin one or more compound(s) selected from compounds represented by formula (I), wherein R1, R2, R3, R4, and R5 independently represent a hydrogen atom or an alkyl group having 1 to 4 carbon atoms; and R represents a hydrogen atom, an acyl group, or a sugar residue.

Afin de fournir un agent externe pour la peau destiné à être utilisé sans risque pour prévenir et améliorer efficacement la pigmentation cutanée sans pour autant agresser la peau, l'invention consiste à ajouter à un agent externe pour la peau un ou plusieurs composé(s) choisi(s) parmi les composés représentés par la formule (I), dans laquelle R¿1?, R¿2?, R¿3?, R¿4? et R¿5? représentent indépendamment un atome d'hydrogène ou un groupe alkyle avec 1 à 4 atomes de carbone; et R représente un atome d'hydrogène, un groupe acyle, ou le reste d'un sucre.

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