Benzo(b)thiepine-1,1-dioxide derivatives, a process for...

C - Chemistry – Metallurgy – 07 – D

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C07D 337/08 (2006.01) A61K 31/38 (2006.01) A61P 3/06 (2006.01) A61P 9/10 (2006.01)

Patent

CA 2334775

The invention relates to substituted benzo(b)thiepine-1,1-dioxide derivatives and to the acid addition salts thereof. The invention relates to compounds of formula (1), wherein R1, R2, R3, R4, R5 and Z have the cited descriptions, to the physiologically compatible salts, to physiologically functional derivatives, and to a method for the production thereof. The compounds are suited, for example, as hypolipidemic agents.

L'invention concerne des dérivés de benzo(b)thiépine-1,1-dioxyde substitués et leurs sels d'addition d'acide. Elle concerne des composés de la formule (I) dans laquelle R<1>, R<2>, R<3>, R<4>, R<5> et Z ont les significations indiquées, ainsi que leurs sels physiologiquement tolérables et dérivés physiologiquement fonctionnels, ainsi que leur procédé de préparation. Ces composés conviennent par exemple comme agents anti-hypolipidémie.

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