Benzo[b]thiophene derivatives and processes for preparing...

Details Benzo[b]thiophene derivatives and processes for preparing... Benzo[b]thiophene derivatives and processes for preparing...

C - Chemistry, Metallurgy

07

D

C07D 333/56 (2006.01) C07D 235/06 (2006.01) C07D 235/28 (2006.01) C07D 333/54 (2006.01) C07D 333/64 (2006.01)

Patent

CA 2406913

A 3,4-distributed benzo[b]thiophene derivative represented by the general formula (I); and a process for producing a benzo[b]thiophene derivative represented by the formula (I), which comprises producing a compound represented by the general formula (V) from a compound represented by the general formula (IV), producing from the compound (V) a mixture of compounds respectively represented by the following formulae (II) and (III), and producing the target compound from the mixture. (I) (IV) (V) (II) (III) [In the formulae, R1 and R2 each represents halogeno, trihalomethyl, C1-4 alkyl, or C1-4 alkoxy; X represents hydroxyl or halogeno; R3 and R4 each represents hydrogen, halogeno, trihalomethyl, C1-4 alkyl, or C1-4 alkoxy; and R5 represents C1-3 alkyl or trifluoromethyl.] (see formula I) (see formula II) (see formula III) (see formula IV) (see formula V)

L'invention concerne un dérivé de benzo[b]thiophène disubstitué en 3,4 représenté par la formule générale (I), ainsi qu'un procédé de production de ce dérivé consistant à produire un composé représenté par la formule générale (V) à partir d'un composé représenté par la formule générale (IV), à produire à partir du composé (V) un mélange de composés représentés respectivement par les formules (II) et (III), et à produire le composé recherché à partir de ce mélange. [Dans les formules, R¿1? et R¿2? représentent chacun un halogéno, un groupe trihalométhyle, C¿1-4?alkyle, ou C¿1-4 ?alkoxy, X représente un groupe hydroxyle ou un halogéno, R¿1? et R¿4? représentent chacun un hydrogène, un halogéno, un groupe trihalométhyle, C¿1-4 ?alkyle, ou C¿1-4 ?alkoxy, et R5 représente un groupe C¿1-3 ?alkyle ou trifluorométhyle.]

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