Benzo[c]quinolizine derivatives and their use as 5...

Details Benzo[c]quinolizine derivatives and their use as 5... Benzo[c]quinolizine derivatives and their use as 5...

C - Chemistry, Metallurgy

07

D

C07D 455/04 (2006.01) A01N 43/42 (2006.01) A01N 43/90 (2006.01)

Patent

CA 2315055

The present invention refers to benzo[c]quinolizines derivatives, fully and partially saturated, having formula (I), and their pharmaceutically acceptable salts which proves useful for pharmaceutical and agricultural use being capable of inhibiting the 5.alpha.-reductase enzyme either selectively in respect of 5.alpha.R-I and 5.alpha.R-II or on both the iso-enzymes.

L'invention concerne des dérivés de benzo[c]quinolizine, intégralement ou partiellement saturés, de formule (I), et leur sels pharmaceutiquement acceptables, utiles à des fins pharmaceutiques et agricoles et capables d'inhiber la 5.alpha.-réductase soit sélectivement à l'égard de 5.alpha.R-I et 5.alpha.R-II ou sur les deux iso-enzymes à la fois.

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