Benzo(d)isoxazol-3-yl-amine compounds and their use as...

Details Benzo(d)isoxazol-3-yl-amine compounds and their use as... Benzo(d)isoxazol-3-yl-amine compounds and their use as...

C - Chemistry, Metallurgy

07

D

C07D 261/20 (2006.01) A61K 31/423 (2006.01) A61K 31/4439 (2006.01) A61P 29/00 (2006.01) C07D 413/04 (2006.01) C07D 413/12 (2006.01)

Patent

CA 2608386

The substituted benzo(d)isoxazol-3-yl-amine compounds of general formula (I) are suitable for treating pains and have an excellent affinity to vanilloid receptor subtype 1 (VR1/TRPV1 receptor) and are therefore especially useful in the prophylaxis and/or treatment of disorders or diseases that are at least partially mediated by vanilloid receptor 1 (VR1/TRPV1).

On a constaté que des composés substitués benzo(d)isoxazol-3-yl-amine de formule (I) sont adaptés au traitement de la douleur et présentent également une excellente affinité avec le récepteur vanilloïde de sous-type 1 (récepteur VR1/TRPV1), ces composés étant donc particulièrement utiles à la prophylaxie et/ou au traitement de troubles ou de maladies associés au moins en partie à des récepteurs vanilloïdes 1 (VR1/TRPV1).

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