Benzo[d]isoxazol-3-yl-piperazin derivatives useful as...

C - Chemistry – Metallurgy – 07 – D

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C07D 413/04 (2006.01) A61K 31/496 (2006.01) A61P 25/00 (2006.01)

Patent

CA 2736724

The present invention relates to compounds of the general formula (I), having affinity and selectivity for the dopamine D3 receptors, their manufacture, pharmaceutical compositions containing them and their use as medicaments. The active compounds of the present invention are useful for the therapeutic and/or prophylactic treatment of cognitive disorders.

La présente invention concerne des composés représentés par la formule générale (I), présentant une affinité et une sélectivité pour les récepteurs D3 de la dopamine, leur fabrication, des compositions pharmaceutiques les cotenant et leur utilisation en tant que médicaments. Les composés actifs de la présente invention sont utiles pour le traitement thérapeutique et/ou prophylactique de troubles cognitifs.

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