Benzo-fused cycloalkane and oxa- and thia-, cycloalkane...

C - Chemistry – Metallurgy – 07 – C

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C07C 233/41 (2006.01) A61K 31/16 (2006.01) A61K 31/40 (2006.01) C07D 295/135 (2006.01) C07D 295/14 (2006.01)

Patent

CA 1341024

Benzo-fused cycloalkane and oxa- and thia- cycloalkane trans-1,2-diamine compounds of the formula: Image wherein A, H, C, D, n, X, Y, R, R1, R2 and R3 are as defined in the specification, e.g., trans-3,4-dichloro-N-methyl-N-[2-(pyrrolidin-1-yl)-5-methoxy- 1,2,3,4-tetrahydronaphth-1-yl]benzeneacetamide, and the pharmaceutically acceptable salts or N-oxides thereof, are useful as analgesics end/or diuretics.

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