Benzoate derivatives of diaryl 1,3,4-oxadiazolone

Details Benzoate derivatives of diaryl 1,3,4-oxadiazolone Benzoate derivatives of diaryl 1,3,4-oxadiazolone

C - Chemistry, Metallurgy

07

D

C07D 271/113 (2006.01) A61K 31/41 (2006.01) C07D 271/07 (2006.01)

Patent

CA 2318814

The present invention provides novel benzoate derivatives having general formula (1), wherein R is as defined herein, or a nontoxic pharmaceutically acceptable salt or solvate thereof and are useful in the treatment of disorders which are responsive to the opening of potassium channels.

Cette invention, qui a trait à de nouveaux dérivés benzoate correspondant à la formule générale (1) dans laquelle R est tel que défini dans le descriptif, concerne également un sel ou un solvate, non toxique et acceptable du point de vue pharmaceutique, de ces dérivés. Ces substances sont efficaces dans le cadre du traitement d'affections influencées par l'ouverture des canaux potassium.

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