Benzoaxozole derivative

Details Benzoaxozole derivative Benzoaxozole derivative

C - Chemistry, Metallurgy

07

D

C07D 413/06 (2006.01) A61K 31/445 (2006.01)

Patent

CA 2270359

The compound 6-{3-[4-(fluorobenzyle)-piperidine-1-yl]-propionyl}-3H- benzoxazole-2-one having formula (I) and its physiologically acceptable salts. Said compound can be used as an excitatory amino acid antagonist to combat neurodegenerative diseases including cerebrovascular diseases, epilepsy, schizophrenia, Alzheimer's disease, Parkinson's disease or Huntingdon's disease, cerebral ischemias, heart infarctions or psychoses.

L'invention concerne un composé 6-{3-[4-(4-fluorobenzyl)-pipéridin-1-yle]-propionyle}3H-benzoxazol-2-one de la formule (I), ainsi que ses sels non toxiques sur le plan physiologique. Ce composé peut s'utiliser comme antagoniste d'aminoacides excitatoire pour lutter contre des affections neurodégénératives, y compris des maladies cérébrovasculaires, l'épilepsie, la schizophrénie, la maladie d'Alzheimer, la maladie de Parkinson ou la chorée de Huntington, les ischémies cérébrales, l'infarctus ou des psychoses.

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