Benzoazine mono-n-oxides and benzoazine 1,4 dioxides and...

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 253/10 (2006.01) A61K 31/517 (2006.01) A61K 31/53 (2006.01) A61K 31/5375 (2006.01) A61K 31/5377 (2006.01) A61P 35/00 (2006.01) C07D 253/08 (2006.01)

Patent

CA 2456569

The present invention relates to a synergetistic composition comprising one or more benzoazine-mono-N-oxides, and one or more benzoazine 1,4 dioxides for use in cancer therapy. The invention also provides a range of novel 1,2,4 benzoazine-mono-N-oxides and related analogues. These can be used as potentiators of the cytotoxicity of existing anticancer drugs and therapies for cancer treatment.

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