Benzocycloheptenes, process for their production,...

C - Chemistry – Metallurgy – 07 – C

Patent

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C07C 317/18 (2006.01) A61K 31/10 (2006.01) A61K 31/133 (2006.01) A61K 31/165 (2006.01) A61K 31/341 (2006.01) A61K 31/381 (2006.01) A61K 31/4402 (2006.01) C07C 217/18 (2006.01) C07C 217/20 (2006.01) C07C 317/28 (2006.01) C07C 317/44 (2006.01) C07C 323/12 (2006.01) C07C 323/25 (2006.01) C07C 323/60 (2006.01) C07C 327/28 (2006.01) C07D 213/32 (2006.01) C07D 213/34 (2006.01) C07D 307/38 (2006.01) C07D 333/18 (2006.01)

Patent

CA 2337991

This invention describes the new benzocycloheptenes of general formula (I): (see formula I) in which R1, R2 and SK have the meanings that are indicated in the description. The new compounds have selective estrogenic activity on bones and are suitable for the production of pharmaceutical agents, especially for prophylaxis and therapy of osteoporosis.

L'invention concerne les nouveaux benzocycloheptènes représentés par la formule générale I (I) dans laquelle R<1>, R<2> et SK sont conformes au descriptif. Ces nouveaux composés ont une action oestrogénique sélective au niveau des os et conviennent pour la préparation de médicaments destinés notamment à la prévention et au traitement de l'ostéoporose.

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