Benzocycloheptyl analogs having sphingosine 1-phosphate...

Details Benzocycloheptyl analogs having sphingosine 1-phosphate... Benzocycloheptyl analogs having sphingosine 1-phosphate...

C - Chemistry, Metallurgy

07

C

C07C 215/28 (2006.01) A61K 31/135 (2006.01) A61P 3/10 (2006.01) A61P 11/06 (2006.01) A61P 19/02 (2006.01) A61P 25/02 (2006.01) A61P 27/02 (2006.01) A61P 37/00 (2006.01) A61P 37/06 (2006.01) C07C 215/38 (2006.01)

Patent

CA 2669124

Benzocycloheptyl analogs that have agonist activity at one or more of the S IP receptors are provided. The compounds are sphingosine analogs, which, after phosphorylation, can behave as agonists at SlP receptors.

La présente invention concerne des analogues benzocycloheptyle ayant une activité d'agoniste au niveau d'un ou plusieurs récepteurs de S1P. Les composés sont des analogues sphingosine, lesquels, après phosphorylation, peuvent se comporter en tant qu'agonistes au niveau des récepteurs de S1P.

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