Benzodiazepine derivative

C - Chemistry – Metallurgy – 07 – D

Patent

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260/239.4

C07D 487/04 (2006.01)

Patent

CA 1214774

ABSTRACT OF THE DISCLOSURE Benzodiazepine derivative represented by the following general formula or pharmaceutically acceptable salt thereof: Image wherein R1 is -COR4 (R4 is a carboxylic acid residue) or an alkyl or aralkyl group (these groups have a substituent selected from a carboxyl group, an amino group and a cyano group), R2 is a lower alkyl group and R3 is a hydrogen atom or a lower alkyl group. The above compound is low in toxicity and has an antitumor activity.

446695

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