Benzodiazepine derivatives

Details Benzodiazepine derivatives Benzodiazepine derivatives

C - Chemistry, Metallurgy

07

D

260/240.3

C07D 243/26 (2006.01) C07D 243/24 (2006.01)

Patent

CA 1157855

ABSTRACT The novel benzodiazepine derivatives of the general formula Image I wherein A signifies the group Image Image Image (a) (b) or (c), and R1, R2, R3, R4, R5, R6' and R7' have the significance given in claim 1, have pronounced aldosterone-antagonistic properties and are suitable for the control or prevention of heart failure, hepatic ascites, primary aldosteronism and idiopathic hypertension. They can be manufactured starting from intermediates, which are to some extent novel, according to various processes. Their use as medicaments is described.

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