Benzodiazepine derivatives

C - Chemistry – Metallurgy – 07 – D

Patent

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Details

C07D 243/24 (2006.01) A61K 31/55 (2006.01) C07D 401/06 (2006.01) C07D 403/04 (2006.01) C07D 403/06 (2006.01) C07D 405/06 (2006.01) C07D 409/06 (2006.01) C07D 413/06 (2006.01) C07D 417/06 (2006.01)

Patent

CA 2099672

2099672 9211246 PCTABS00014 A novel benzodiazepine derivative represented by general formula (I), a pharmaceutically acceptable salt thereof, a pharmaceutical composition thereof, and a process for producing the same. In formula (I), R1 represents optionally substituted aryl, five-membered monocyclic group, six-membered monocyclic group or aromatic heterocyclic group comprising five-membered and six-membered rings; and R2 represents optionally substituted aryl. The compound (I) has a CCK-B receptor antagonism and an action of inhibiting pentagastrin-stimulated gastric secretion and hence is useful in treating and preventing the diseases wherein a CCK-B receptor and a gastrin receptor participate.

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