Benzodiazepine derivatives, compositions containing them and...

Details Benzodiazepine derivatives, compositions containing them and... Benzodiazepine derivatives, compositions containing them and...

C - Chemistry, Metallurgy

07

D

C07D 413/12 (2006.01) A61K 31/55 (2006.01) C07D 403/12 (2006.01) C07D 413/14 (2006.01) C07D 417/12 (2006.01)

Patent

CA 2130195

2130195 9319063 PCTABS00025 Compounds of formula (I), and salts and prodrugs thereof wherein: R1 is H, certain optionally substituted C1-6alkyl, or C3-7cycloalkyl; R2 represents a group (a) wherein X is O, S or NR8 where R8 is H or C1-4alkyl; one of Z and Y is C=O and the other is O, S or NR9, where R9 is H or C1-4alkyl; R3 is C1-6alkyl, halo or NR6R7; R4 is C3-10cycloalkyl; n is 0, 1, 2, or 3; are CCK and/or gastrin receptor antagonists. They and compositions thereof are useful in therapy.

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