Benzodiazepine derivatives, compositions containing them and...

Details Benzodiazepine derivatives, compositions containing them and... Benzodiazepine derivatives, compositions containing them and...

C - Chemistry, Metallurgy

07

D

C07D 403/04 (2006.01) A61K 31/55 (2006.01) A61K 31/69 (2006.01) C07D 243/14 (2006.01) C07D 401/04 (2006.01) C07D 403/12 (2006.01) C07D 403/14 (2006.01) C07D 405/12 (2006.01) C07D 405/14 (2006.01) C07D 413/04 (2006.01) C07D 417/04 (2006.01) C07F 5/02 (2006.01)

Patent

CA 2119875

2119875 9308176 PCTABS00021 Compounds of formula (I), and salts and prodrugs thereof, wherein X is O, S, NR4 or CH2; R1 represents H, certain optionally substituted C1-6 alkyl, or C3-7 cycloalkyl; R2 represents phenyl having certain optional substituents; R3 represents C1-6 alkyl, halo or NR6R7; m is 2, 3 or 4; n is 1, 2, 3, 4, 5, 6, 7 or 8 when X is CH2 or 2, 3, 4, 5, 6, 7 or 8 when X is O, S or NR4; and x is 0, 1, 2 or 3; are CCK and/or gastrin antagonists. They and compositions thereof are therefore useful in therapy.

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