Benzodiazepine derivatives, compositions containing them and...

Details Benzodiazepine derivatives, compositions containing them and... Benzodiazepine derivatives, compositions containing them and...

C - Chemistry, Metallurgy

07

D

C07D 403/12 (2006.01) A61K 31/55 (2006.01) C07D 401/14 (2006.01) C07D 405/12 (2006.01) C07D 409/12 (2006.01) C07D 409/14 (2006.01)

Patent

CA 2085656

T1135Y ABSTRACT BENZODIAZEPINE DERIVATIVES, COMPOSITIONS CONTAINING THEM AND THEIR USE IN THERAPY Compounds of formula (I), and salts and prodrugs thereof Image (I) wherein: R1 is H, certain optionally substituted C1-6alkyl, or C3-7cyclocalkyl; R2 represents a group Image wherein X is O, S or NR8 where R3 is H or C1-4alkyl; R3 is C1-6alkyl, halo or NR6R7; R4 is C1-7alkyl, C3-7cycloalkyl, C4-7cycloalkylalkyl or optionally substituted aryl; n is O, 1, 2 or 3; are CCK and/or gastrin receptor antagonists. They and compositions thereof are useful in therapy.

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