C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 243/12 (2006.01) A61K 31/55 (2006.01) A61P 43/00 (2006.01) C07D 401/04 (2006.01) C07D 401/06 (2006.01) C07D 401/14 (2006.01) C07D 403/10 (2006.01) C07D 405/04 (2006.01) C07D 405/06 (2006.01) C07D 409/04 (2006.01) C07D 413/10 (2006.01) C07D 417/04 (2006.01) C07D 417/06 (2006.01) C07D 417/10 (2006.01) C07D 417/14 (2006.01) C07F 7/10 (2006.01)
Patent
CA 2386980
The present invention relates to compounds of general formula (I) wherein R3 is phenyl; pyridine; thiophenyl or thiazolyl, which are optionally substituted. The com-pounds according to the present invention can be used for treating or preventing acute and/or chronic neurological disorders such as psychosis, schizophrenia, Alzheimer's disease, cog-nitive disorders and memory deficits.
L'invention concerne des composés correspondant à la formule générale (I) dans laquelle R<3> représente phényle, pyridine, thiophényle ou triazolyle éventuellement substitués. Selon l'invention, les composés peuvent être utilisés pour traiter ou prévenir des troubles neurologiques chroniques et/ou aigus, tels que la psychose, la schizophrénie, la maladie d'Alzheimer, des troubles cognitifs et des déficiences de la mémoire.
Adam Geo
Alanine Alexander
Goetschi Erwin
Mutel Vincent
Woltering Thomas Johannes
Borden Ladner Gervais Llp
F. Hoffmann-La Roche Ag
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