Benzodiazepine derivatives, preparation thereof and use thereof

Details Benzodiazepine derivatives, preparation thereof and use thereof Benzodiazepine derivatives, preparation thereof and use thereof

C - Chemistry, Metallurgy

07

D

C07D 243/24 (2006.01) A61K 31/5513 (2006.01) C07D 401/04 (2006.01) C07D 401/14 (2006.01) C07D 403/04 (2006.01) C07D 403/14 (2006.01) C07D 405/14 (2006.01) C07D 409/04 (2006.01)

Patent

CA 2468448

Compounds of Formula (I) wherein R1, R3, R4, R5 and X are as defined in the specification, as well as salts, enantiomers thereof and pharmaceutical compositions including the compounds are prepared. They are useful in therapy, in particular in the management of pain.

L'invention concerne des composés de formule (I) dans laquelle R?1¿, R?3¿, R?4¿, R?5¿ et X sont tels que définis dans la description, ainsi que des sels et des énantiomères de ces composés, des compositions pharmaceutiques renfermant lesdits composés, et la préparation de ces produits. Les composés selon l'invention sont utilisés en thérapie, en particulier pour le traitement de la douleur.

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