Benzodiazepines

Details Benzodiazepines Benzodiazepines

C - Chemistry, Metallurgy

07

D

C07D 403/04 (2006.01) A61K 31/55 (2006.01) C07D 401/14 (2006.01) C07D 403/14 (2006.01)

Patent

CA 2098063

RAN 4430/51 ABSTRACT The benzodiazepines of formula Image I where X and Y are each independently selected from H, halogen, and lower alkyl; R10 and R11 are both H, or one of R10 and R11 is H and the other is methyl, or R10 and R11 together are -(CH2)n- where n = 4 or 5; Z is a ring selected from the group consisting of Image Image or Image (Z1) (Z2) (Z3) where one or more carbon atoms in said ring Z can be substituted by P, Cl or lower alkyl; as well as the pharmaceutically acceptable acid addition salts, carbamates, ureas and amides thereof can be used as therapeutically active agent, especially as antiviral agents, particularly for the treatment, therapy or prophylaxis of AIDS and AIDS-related diseases.

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