Benzodiazepines assay, tracers, immunogens and antibodies

Details Benzodiazepines assay, tracers, immunogens and antibodies Benzodiazepines assay, tracers, immunogens and antibodies

C - Chemistry, Metallurgy

07

D

260/240, 167/43,

C07D 243/24 (2006.01) C07D 493/10 (2006.01) G01N 33/533 (2006.01) G01N 33/542 (2006.01) G01N 33/94 (2006.01)

Patent

CA 1339439

The present invention is directed to a fluorescence polarization assay for benzodiazepines and their metabolites, to the various components needed for preparing and carrying out such an assay and to methods of making these components. Specifically, tracers, immunogens and antibodies are disclosed, as well as methods for making them. The assay is conducted by measuring the degree of polarization retention of the fluorescence resulting when a sample mixed with antiserum and tracer is irradiated with plane-polarized light.

550168

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