Benzodiazepinone compounds useful in the treatment of skin...

C - Chemistry – Metallurgy – 07 – D

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C07D 243/18 (2006.01) C07D 243/10 (2006.01) C07D 243/12 (2006.01)

Patent

CA 2703005

The present invention provides a family of benzodiazepinone compounds and pharmaceutical compositions thereof. The present invention also provides methods of treating certain skin conditions, e.g., atopic dermatitis, rosacea, or psonasis, by administering a benzodiazepinone and methods of reducing the proliferation of keratinocyte cells by exposing such cells to a benzodiazepinone.

L'invention concerne une famille de composés benzodiazépinone et leurs compositions pharmaceutiques. L'invention concerne également des procédés de traitement de certaines affections de la peau, par exemple, la dermite atopique, l'acné rosacée ou le psoriasis, par l'administration d'une benzodiazépinone et des procédés de réduction de la prolifération de cellules de kératinocyte par l'exposition de ces cellules à une benzodiazépinone.

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