C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
260/239.5
C07D 487/04 (2006.01) C07D 239/42 (2006.01)
Patent
CA 1157018
173 Wo 8/80 ABSTRACT . Benzodiazepinones of the general formula I (I) Image wherein R denotes a hydrogen atom or a phenyl group, R1 de- notes a hydrogen atom or an alkyl radical with 1 to 4 carbon atoms, R2 denotes the group -Co-CnH2nR3 or (when R is a phe- nyl group) a hydrogen atom, R3 denotes a halogen atom or the group -N(R4)R5, R4 denotes an alkyl radical with 1 to 4 car- bon atoms or an alkenyl radical with 3 to 5 carbon atoms, R5 denotes an alkyl radical with 1 to 4 carbon atoms, which may be substituted by a dialkylamino group with 1 to 4 carbon atoms in the alkyl radicals, or an alkenyl radical with 3 to 5 carbon atoms, or R4 and R5 together, and including the nitrogen atom, denote a pyrrolidino, piperidino, morpholino or perhydroazepino radical, a piperazino radical which is optionally substituted in the 4-position by a methyl, ethyl or benzyl group or a homopiperazino radical which is optional- ly substituted in the 4-position by a methyl group, and n re- presents 1 or 2, and their N-oxides and their acid addition salts with inorganic and organic acids are new compounds. They are used in the pharmaceutical industry as intermediate products and for the preparation of medicaments with protec- tive action on the stomach and the intestines.
357697
Byk Gulden Lomberg Chemische Fabrik G.m.b.h.
Fetherstonhaugh & Co.
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