Benzodioxane and benzodioxolane derivatives and uses thereof

Details Benzodioxane and benzodioxolane derivatives and uses thereof Benzodioxane and benzodioxolane derivatives and uses thereof

C - Chemistry, Metallurgy

07

D

C07D 319/20 (2006.01)

Patent

CA 2648612

The present invention relates to methods for synthesizing compounds of formula (I) or pharmaceutically acceptable salts thereof: Formula (I) wherein each of R1, R2, R3, R4, x, m, n, and Ar are as defined, and described in classes and subclasses herein, which are agonists or partial agonists of the 2C subtype of brain serotonin receptors.

La présente invention concerne des procédés de synthèse des composés de formule (I) et de leurs sels pharmaceutiquement acceptables : Formule (I) dans laquelle R1, R2, R3, R4, x, m, n et Ar sont chacun tels que définis et décrits dans les classes et sous-classes du présent mémoire. Lesdits composés et leurs sels pharmaceutiquement acceptables sont des agonistes ou des agonistes partiels du sous-type 2C des récepteurs de la sérotonine dans le cerveau.

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