Benzofuran- and benzopyran-carboxamide derivatives

C - Chemistry – Metallurgy – 07 – D

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167/207, 260/363

C07D 307/84 (2006.01) C07D 307/79 (2006.01) C07D 405/12 (2006.01) C07D 413/12 (2006.01)

Patent

CA 1238906

ABSTRACT BENZOFURAN- AND BENZOPYRAN-CARBOXAMIDE DERIVATIVES Benzofuran- and benzopyran-carboxamide derivatives of the formula: Image wherein ? is 1 or 2; X is hydrogen atom, amino group or halogen atom; Y is -S(O)m-R3 wherein R3 is lower alkyl group and m is 0, 1, or 2, or Image wherein R4 and R5 are the same or different and are each hydrogen atom or lower alkyl group; R1 is hydrogen atom, lower alkyl group, arylthiomethyl group, halogenomethyl group or Image wherein R6 and R7 are the same or different and are each hydrogen atom or lower alkyl group or R6 and R7 together with the adjacent nitrogen atom form a heterocycle; R2 is hydrogen atom or lower alkyl group; and Z is Image wherein p is 2 or 3, R8 and R9 are the same or different and are each lower alkyl group or R8 and R9 together with the adjacent nitrogen atom form a heterocycle, or Image wherein q is 0 or 1, n is 1 or 2, R10 is lower alkyl group, lower alkenyl group, lower alkinyl group, aralkyl group or cycloalkyl group and R11 is hydrogen atom or lower alkyl group, their physiologically acceptable salts or their optical isomers, and a method of preparing same. These compounds are useful as psychotropic and anti- psychotic agents.

450167

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