Benzofuran, benzothiophene containing lipoxygenase...

Details Benzofuran, benzothiophene containing lipoxygenase... Benzofuran, benzothiophene containing lipoxygenase...

C - Chemistry, Metallurgy

07

D

167/242, 167/245

C07D 307/81 (2006.01) A61K 31/38 (2006.01) C07D 333/60 (2006.01)

Patent

CA 1327204

Compounds of the formula Image . wherein R2 and R3 are independently selected from hydrogen, or C1-2 alkyl; wherein X is oxygen, or sulfur; and M is hydrogen, or a pharmaceutically acceptable cation, are potent inhibitors of 5- and/or 12-lipoxygenase enzymes. Also disclosed are lipoxygenase inhibiting compositions and a method for inhibiting lipoxygenase activity.

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