C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 307/80 (2006.01) A61K 31/34 (2006.01)
Patent
CA 2112890
ABSTRACT The present invention relates to a compound expressed by the following general formula (I), pharmacologically- acceptable salt thereof and pharmaceutical composition mainly comprising the same. Image [I] wherein R1 is hydrogen, halogen or alkyl R2 is alkoxycarbonyl, aralkyloxycarbonyl, carboxy, hydroxyalkyl or acyloxyalkyl: Y is >CHOH, >CHOZ, >CH2 or >CO; and z is acyl. The pharmaceutical composition of the present invention is effective for prevention and therapy of arteriosclerosis, ischemic heart diseases, cerebral infarction and restenosis after PTCA operations.
Chokai Shoichi
Ohmachi Shinji
Taira Masafumi
Nippon Shinyaku Co. Ltd.
Osler Hoskin & Harcourt Llp
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