C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
167/207, 260/270
C07D 307/79 (2006.01) C07C 43/225 (2006.01) C07D 405/12 (2006.01) C07D 451/04 (2006.01)
Patent
CA 1297877
BENZOFURANCARBOXAMIDES USEFUL AS ANTIEMFTIC OR ANTIPSYCHOTIC AGENTS ABSTRACT Benzofurancarboxamides represented by the formula (I): Image I wherein Z represents the structural formula Image wherein the dotted line represents two hydrogen atoms or another bond, the benzo [b] furan ring or dihydrobenzo [b] furan ring being completed by Z being either unsubstituted or substituted at the 2- or 3-position by a lower alkyl group; R1, R2 and R3 may be the same or different and represent a hydrogen atom, an alkyl group having 1 to 6 carbon atoms, an alkoxy group having 1 to 6 carbon atoms, a halogen atom, an amino group, an alkylamino group, a nitro group, an acylamido group having 1 to 6 carbon atoms, and a sulfonamido group having up to 6 carbon atoms; and A represents an amino alkyl group; and pharmaceutical preparations containing the same. The above-defined benzofuran-carboxamides are used as antiemetic and/or antipsychotic agents.
467214
Lednicer Daniel
Sun Jung-Hui
Adria Laboratories Inc.
Gowling Lafleur Henderson Llp
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