Benzofurans and a novel method of preparation

Details Benzofurans and a novel method of preparation Benzofurans and a novel method of preparation

C - Chemistry, Metallurgy

07

D

260/361.1

C07D 307/79 (2006.01)

Patent

CA 1291487

-0- NOVEL BENZOFURANS AND A NOVEL METHOD OF PREPARATION ABSTRACT There are disclosed novel benzofurans having the following structural formula: Image wherein R is alkenyl of 1 to 6 carbon atoms or aryl of from 6 to 10 carbon atoms; R1 is H, alkali metal, or alkyl of 1 to 4 carbon atoms; and R2 is alkyl or alkoxy of from 1 to 5 carbon atoms, hydrogen, amino or dialkylamino, nitro, sulfonyl, alkyl or aryl thioether or halo. Also disclosed is a novel process of making the benzofurans, comprising the step of cyclizing an o-(2-carboxyvinyl)phenyl unsaturated alkyl ether in the presence of a base selected from the group consisting of KOH, NaOH, LiOH, dimsyl sodium, lithium diisopropylamide, potassium text-butoxide, and mixtures thereof, at room temperature. The benzofurans are useful starting materials in forming acetamidine derivatives having pharmacological utility.

544664

Affiliated with

Also associated with

Rating

Benzofurans and a novel method of preparation does not yet have a rating. At this time, there are no reviews or comments for this patent.

If you have personal experience with Benzofurans and a novel method of preparation, we encourage you to share that experience with our LandOfFree.com community. Your opinion is very important and Benzofurans and a novel method of preparation will most certainly appreciate the feedback.

Rate now

Comments { 0 }

Profile ID: LFCA-PAI-O-1277702