Benzofuranyl- and thiophenylmethylthio-alkanecarboxylic acid...

C - Chemistry – Metallurgy – 07 – D

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C07D 307/80 (2006.01) A61K 31/34 (2006.01) A61K 31/38 (2006.01) A61K 31/44 (2006.01) A61K 31/495 (2006.01) C07D 333/56 (2006.01) C07D 333/60 (2006.01) C07D 405/02 (2006.01) C07D 409/02 (2006.01) C07D 413/02 (2006.01) C07D 417/02 (2006.01)

Patent

CA 2086987

Benzofuranyl- and thiophenylmethylthio-alkanecarboxylic acid derivatives A b s t r a c t Benzofuranyl- and thiophenylmethylthio-alkanecarboxylic acid derivatives are prepared by brominating appropriate methyl compounds and reacting the methyl bromides thus obtained with mercapto-alkanecarboxylic acid derivatives. The new substances are suitable as NADPH oxidase inhibitors for use in medicaments, in particular for the treatment of acute and chronic inflammatory precesses. Le A 28 658

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