Benzofuranylmethyphenyl derivatives

C - Chemistry – Metallurgy – 07 – D

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260/361.1, 260/3

C07D 307/78 (2006.01) C07D 307/83 (2006.01) C07D 307/92 (2006.01) C07D 405/02 (2006.01)

Patent

CA 1212678

BENZOFURANYLMETHYLPHENYL DERIVATIVES ABSTRACT OF THE INVENTION Compounds of the following formula are disclosed Image (I) in which R1, R2, R3, R4, R5 and R6 are the same or different and are hydrogen, halogen, C1-4 alkyl, C1-4 alkoxy, C3-8 cycloalkyl, phenyl, phenyl substituted with 1 to 3 substituents selected from methyl, methoxy, halogen and nitro, C1-4 haloalkyl, C1-4 acylamino, C1-4 alkylaminocarbonyl, amino, cyano,hydroxy, nitro, C3-4 alkenyl, C3-4 alkenyloxy, carboxy C1-2 alkoxy, carboxyl, tetrazol-5-yl or carboxyvinyl, or R1 and R2 taken together at adjacent carbon atoms represent a phenyl ring; or a salt or ester thereof. The compounds have pharmaceutical activity.

442440

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