C - Chemistry – Metallurgy – 07 – D
Patent
C - Chemistry, Metallurgy
07
D
C07D 519/00 (2006.01) A61K 31/519 (2006.01) A61K 31/551 (2006.01) A61P 29/00 (2006.01) C07D 491/048 (2006.01) C07D 491/147 (2006.01) C07D 495/04 (2006.01) C07D 495/14 (2006.01)
Patent
CA 2657908
Benzofuro- and benzothienopyrimidine compounds are described, which are useful as H4 receptor modulators. Such compounds may be used in pharmaceutical compositions and methods for the treatment of disease states, disorders, and conditions mediated by H4 receptor activity, such as allergy, asthma, autoimmune diseases, and pruritis.
L'invention concerne des composés de benzofuro et benzothiénopyrimidine, qui sont utiles en tant que modulateurs du récepteur H4. De tels composés peuvent être utilisés dans des compositions pharmaceutiques et des procédés de traitement d'états, de troubles et de conditions pathologiques induits par l'activité du récepteur H4, tels que les allergies, l'asthme, les maladies auto-immunes et le prurit.
Chavez Frank
Curtis Michael P.
Edwards James P.
Fitzgerald Anne E.
Gomez Laurent
Janssen Pharmaceutica N.v.
Norton Rose Or S.e.n.c.r.l. S.r.l./llp
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