Benzoic acid and benzoic acid ester derivatives having...

C - Chemistry – Metallurgy – 07 – C

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167/233, 167/260

C07C 233/51 (2006.01) A61K 31/195 (2006.01) C07D 257/04 (2006.01)

Patent

CA 1277326

ABSTRACT Novel benzoic acid or benzoic acid ester derivatives, pharmaceutical compositions and methods of use thereof are the present invention. Utility is for the treatment of arthritis, asthma, Raynaud's disease, inflammatory bowel disorders, trigeminal or herpetic neuralgia, inflammatory eye disorders, psoriasis, dental pain, and headaches, particularly vascular headache, such as migraine, cluster, mixed vascular syndromes, as well as nonvascular, tension headaches. The novel compounds have the general formula: Image wherein B, Q, R1, R2, X and Y are as defined in the disclosure and claims.

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